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a more favorable option for some patients Side Effects: Black Box Warning: RISK OF THYROID C-CELL TUMORS Reference: rxlist.com (Tanzeum) Dulaglutide Drug Name: Trulicity (FDA Approved 9/18/14) GLP-1 receptor agonist, hypoglycemic Pharmacokinetics: Long acting (half life: 5 days) subcutaneous pen injections weekly dosing (vs daily dosing for some other GLP-1 agonists such as exenatide, liraglutide & lixisenatide) a more favorable dosing option for some patients Side Effects: Black Box Warning: RISK OF THYROID C-CELL TUMORS References: Masharani U, Kroon L (2024): Pancreatic Hormones & Antidiabetic Drugs (Chapter 41)

The native peptide 1 had an IPGTT curve similar to the vehicle as expected from previous studies